Estudio de la mielinogénesis en el sistema nervioso periférico en condiciones fisiológicas y patológicas. Participación de células pluripotentes en el proceso de degeneración-regeneración nerviosa.
Directora: Patricia Setton Avruj
Rocío Martinez Vivot, Belén Goitia, Vanina Usach and Patricia Setton-Avruj. DMT1 as a candidate for non-transferrin-bound iron uptake in the peripheral nervous system”. Biofactors (2013) 39 (4): 476-484. PubMed
Salis, C.,Usach V, Davio C, Urtasun N, Goitia B, Martinez-Vivot R, Pasquini, J.M.and CP Setton-Avruj. Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells. Neurochemistry International (2012) 61 798–806. PubMed
Vanina Usach, Belén Goitia, Lucía Lavalle, Rocío Martinez Vivot and Patricia Setton-Avruj. Bone marrow mononuclear cells migrate to the demyelinated sciatic nerve and transdifferentiate into Schwann cells: an attempt at an endogenous repair mechanism after nerve injury”.. Journal of Neuroscience Research (2011) 89:1203–1217. PubMed
Setton-Avruj C.P., Musolino P.L., Salis C, Alló M, Bizzozero O, Villar M.J., Soto E.F and Pasquini J.M. Presence of alpha-globin mRNA and migration of bone marrow cells after sciatic nerve injury suggests their participation in the degeneration/regeneration process. Exp Neurol. (2007) 203(2):568-78. PubMed
JB Aquino, MF Coronel, MJ Villar and CP Setton-Avruj. Nerve degeneration is prevented by a single intraneural apotransferrin injection into colchicine injured sciatic nerves in the rat. Brain Res. (2006) 1117(1):80-91. PubMed